RESEARCH PROJECTS

June 1993 to June 1996:

1. Coronary and peripheral vascular endothelial dysfunction – Supervisor, Arshed A. Quyyurni, MD; Chief cardiac catherization laboratory, Cardiology Branch National Institutes of Health, Bethesda, MD
2. Prognostic significance of transient ischernia detected by noninvasive testing in patients with documented coronary artery disease – Supervisor, David Mulcahy, MD, Cardiology Branch National Institutes of Health, Bethesda, MD

July 1997 to July 1998:

Principal Investigator:

1. Heart rate variability and prediction of post-operative cardiac complications after vascular surgery
2. Heart rate variability and beta-blockade in congestive heart failure
3. Cholesterol lowering therapy and anti-anginal effects

Participation in Clinical Trials:

  • Presto
  • Fusion
  • Target
  • Verapramil in coronary saphenous vein graft intervention
  • Tactics/TIMI18

Participation in animal cardiac catheterization laboratory:

  • Left heart catheterization, coronary velocity reserve, guidewire efficacy and effects of various drugs on coronary physiological reserve

Research Techniques:

  • Quantitative Coronary Angiography
  • Forearm and thigh venous impedance plethsmography
  • Coronary and peripheral vascular blood flow studies (including doppler techniques)
  • Basic science techniques in molecular and cell biology
  • Direct experience in designing and directing clinical trials as principal investigator